Product name: Clavanin-A

Sequence: VFQFLGKIIHHVGNFVHGFSHVF

Modifications: c-terminal amide,

Purity: 95% by HPLC

Counter ion: Trifluoacetate

Format: Lyophilized powder

Description: Clavanin A is a special antimicrobial peptide that acts at the level of the membrane via a pH-dependent mechanism. At neutral pH, clavanin disrupts biological and model membranes in a nonspecific manner, causing efflux of large molecules. At mildly acidic conditions, however, the peptide efficiently kills bacteria by permeabilizing their membrane most likely by interacting with proteins involved in proton translocation .

Uniprot ID: P80710

Usage: For Scientific Research Use Only, Not for Human Use.

Reference:

FEBS Letters, Volume 400, Issue 2, 3 January 1997, Pages 158-162

Biochimica et Biophysica Acta (BBA) - Biomembranes, Volume 1615, Issues 1–2, 2 September 2003, Pages 84-92