Product name: Cyclo(Ala-Gly)

Synonyms: cyclo(L-Ala-Gly),
(S)-3-methylpiperazine-2,5-dione,

Sequence: cyclo(l-Ala-Gly)

Modifications: head-to-tail cyclization,

Purity: 95% by HPLC

Counter ion: Trifluoacetate

Format: Lyophilized powder

Description: Raman optical activity (ROA) measures the different intensity of right- and left-circularly polarized Raman scattered light and provides information on chirality associated with vibrational modes. Because of a high sensitivity to subtle structural and environmental changes, interpretations of ROA spectra usually rely on quantum chemical simulations. Although cyclo(l-Ala-Gly) is a relatively rigid cyclic molecule, boat-up and boat-down conformations were found from the MD calculations. Because the Raman spectra of the two conformations are similar except for a lower frequency region, ∼10 MD snapshots are capable of reproducing the main features of the observed Raman spectra.

Usage: For Scientific Research Use Only, Not for Human Use.

Reference:

J. Phys. Chem. B, 2014, 118 (24), pp 6767–6774.