Product name: Flecainide Acetate

Synonyms: Flecaine, Tambocor, Flecainida, Flecainidum, (+-)-Flecainide,N-(piperidin-2-ylmethyl)-2,5-bis(2,2,2-trifluoroethoxy)benzamide,

Purity: 95% by HPLC

Format: White powder

Description: Flecainide acetate is a class IC antiarrhythmic agent that was first synthesized in 1972. Its development began in 1966 in an attempt to generate new fluorinated anesthetic organic agents with the substitution of a trifluoroethoxy group on the aromatic ring in the place of the amine group. The clinical development program of flecainide provided good data on its antiarrhythmic effect for the prevention of ventricular and supraventricular arrhythmias. The Cardiac Arrhythmia Suppression Trial (CAST), conducted to test whether the arrhythmia suppression translates into prevention of sudden death, assessed the impact of flecainide and encainide therapy in patients with frequent ventricular ectopics and reduced left ventricular function who had survived an infarction.

Compound ID: 3356      

Usage: For Scientific Research Use Only, Not for Human Use.

Reference:

Neth Heart J. 2015 Mar;23(3):180-1.

Circ Res. 2015 Apr 10;116(8):1324-35.

World J Cardiol. 2015 Feb 26;7(2):76-85.

Expert Opin Pharmacother. 2013 Feb;14(3):347-57.