Product name: PEP1261

Synonyms: Boc-Lys (Boc)-Arg-Asp-Ser (tBu)-OtBu

Sequence: Boc-Lys (Boc)-Arg-Asp-Ser (tBu)-OtBu

Purity: 95% by HPLC

Format: White powder

Description: PEP1261, a peptide sequence (39-42) of human lactoferrin. The parent protein lactoferrin is able to inhibit the production of free radicals in rheumatoid joints and it regulates many aspects of inflammation. PEP1261 possesses antiarthritic activity by inhibiting nitrite levels as well as MMP-2 expression. PEP1261 inhibited nitric oxide level in cultured synovial fibroblasts.

Usage: For Scientific Research Use Only, Not for Human Use.

Reference:

Oxid Med Cell Longev. 2013;2013:853210.

Peptides. Volume 27, Issue 6, June 2006, Pages 1434–1442.

Mol Cell Biochem. 2006 Jan;282(1-2):125-39.

Peptides. 2005 Apr;26(4):615-9.

Pharmacology. 2002 May;65(2):103-9.

Mol Cell Biochem. 2002 Jan;229(1-2):9-17.

Inflamm Res. 1999 Sep;48(9):479-84.