Product name:pENW

Synonyms: pGlu-Asn-Trp

Sequence: pGlu-Asn-Trp

Purity: 95% by HPLC

Format: White powder

Description: Platelets play a key role in hemostasis and in the initiation and propagation of thrombus formation. New peptide pGlu-Asn-Trp (pENW), initially extracted from snake venom, shows a concentration-dependent antithrombotic activity, significantly attenuated thrombus formation in the arterial and venous vessel systems. pENW attenuated thrombus formation in part by inhibiting platelet activation instead of coagulation factors, presented evidence of pENW interfering intracellular signaling system in the process of platelet activation and indicated the possibility that pENW could potentially be developed as a novel therapeutic agent in the prevention and treatment of thrombotic disorders.

Usage: For Scientific Research Use Only, Not for Human Use.

Reference:

Eur J Med Chem. 2015 Jul 10;102:363-374.

Eur J Pharm Sci. 2012 Apr 11; 45(5):552-8.

J Pharm Pharmacol. 2009 Jan; 61(1):89-94.