Product name: Vilon

Synonyms: lysylglutamic acid, Lysyl-Glutamate,

Sequence: Lys-Glu

Purity: 95% by HPLC

Format: White powder

Description: The effect of the synthetic peptide bioregulator Vilon on structural and facultative heterochromatin of cultured lymphocytes from old people has been studied. The data obtained indicate that Vilon (a) induces unrolling (deheterochromatinization) of total heterochromatin; (b) activates synthetic processes caused by the reactivation of ribosomal genes as a result of deheterochromatinization of nucleolus organizer regions; (c) releases the genes repressed due to the condensation of euchromatic regions forming facultative heterochromatin; (d) does not induce decondensation of pericentromeric structural heterochromatin. Our results indicate that Vilon causes progressive activation (deheterochromatinization) of the facultative heterochromatin with increased aging.

Compound ID: 7010502

Usage: For Scientific Research Use Only, Not for Human Use.

Reference:

Bull Exp Biol Med. 2015 Mar;158(5):681-3.

Georgian Med News. 2013 Dec;(225):94-7.

Bull Exp Biol Med. 2005 Jan;139(1):24-6.

Biogerontology. 2004;5(2):73-9.

Vopr Onkol. 2002;48(1):57-60.