Product name: AFPep

Synonyms: AFP-derived peptide,

Sequence: cyclo[EKTOVNOGN]

Modifications: O,hydroxyproline; head-to-tail cyclization,

Purity: 95% by HPLC

Format: White powder

Description: AFPep has been shown previously to stop the growth of estrogen-dependent human breast cancer xenografts in mice and prevent carcinogen-induced breast cancer in a rat model. As the anti-oncogenic, anti-estrotrophic active site of AFP, the cyclic 9-mer peptide AFPep has substantial biologic activity that suggests it may be useful in the fight against breast cancer. AFPep is efficacious in vitro and in vivo for therapy and prevention of breast cancer, is well tolerated, and has a unique mechanism of action.

Usage: For Scientific Research Use Only, Not for Human Use.

Reference:

Cancer Prev Res June 2014 7; 565.

Peptides. Volume 32, Issue 12, December 2011, Pages 2504–2510.

Oncol Rep. 2009 Jul; 22(1):49-56.