Product name: Cryptophycin-52

Synonyms: Cryptophycin 52,

Sequence:
Cryptophycin-52, LY355703,

Purity: 95% by HPLC

Format: White powder

Description: Cryptophycin-52, also known as LY355703, is a synthetic analogue of the cryptophycin family produced by total chemical synthesis. In a preclinical study,  reported that cryptophycin-52 induced in vitro Bcl-2 hyperphosphorylation, cell cycle arrest and growth inhibition in human non-small cell lung carcinoma cells. Phase II clinical trials of cryptophycin-52 yielded promising results of antitumor activity in patients with platinum-resistant advanced ovarian cancer and patients with advanced non-small cell lung cancer.

Compound ID: 9939639

Usage: For Scientific Research Use Only, Not for Human Use.

Reference:

Int J Gynecol Cancer. 2006 Jan-Feb; 16(1):71-6.

Lung Cancer. 2003 Feb; 39(2):197-9.

Cancer Chemother Pharmacol. 2001; 47(2):170-8.