Product name: LKPNM

Synonyms: ACE-inhibiting peptide,

Sequence: Leu-Lys-Pro-Asn-Met

Purity: 95% by HPLC

Counter ion: Trifluoacetate

Format: Lyophilized powder

Description: Katsuobushi oligopeptide, a linear pentapeptide from dried bonito (katsuobushi, a traditional Japanese food), was derived from katsuobushi by thermolysin hydrolysis. It manifested ACE inhibitory activity when transformed to the active form in the human digestive system . Katsuobushi oligopeptide exerted antihypertensive activity in patients with hypertension and borderline hypertension in a small-scale clinical trial. Official approval of katsuobushi oligopeptide as foods for specified health use was issued in 1999 by Ministry of Health and Welfare in Japan. Subsequent reports indicated that the peptide brought about relaxation of vascular smooth muscle . They are incorporated in blood pressure-lowering capsules which are sold as nutraceutical .

Usage: For Scientific Research Use Only, Not for Human Use.

Reference:

Immunopharmacology. 1999 Oct 15;44(1-2):123-7.